Irritability can be described as a cognitive effect which results in one experiencing heightened feelings of annoyance, stress, irritability, anger and a tendency towards violent behaviour.

This component most commonly occurs on the offset period of high dosage stimulants such as cocaine. It is often accompanied by feelings of anxiety, paranoia and ego inflation. Irritability may also be a feature of unrecognized bipolar (spectrum) disorder.

The chances of somebody responding negatively to this state and acting aggressive towards others when they would not usually do so differs wildly between people. It is worth noting, however, that most people are very much capable of suppressing these feelings and only those who were previously susceptible to violent or aggressive behaviour are negatively affected.


Adenomyosis is a benign condition of the uterus, defined by the presence of endometrial glands and stroma within the myometrium. Some women with adenomyosis do not experience any symptoms (30%), while others may have severe, debilitating symptoms. Symptoms include intense debilitating pain, strong 'contraction' feel of uterus and other. Adenomyosis has also been linked with anxiety, depression, and irritability.

Hyperthyroidism, Thyroid disorders

Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormone by the thyroid gland. Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea, enlargement of the thyroid, and weight loss.

Anorexia Nervosa

Lifetime comorbidity between Eating Disorders (EDs) and Mood Disorders (MD) has been confirmed by several retrospective studies reporting that in Anorexia Nervosa (AN) the prevalence of mood disorders varies between 64.1% and 96%. Depressed ED patients are not inhibited or melancholic, but tended to show angry depression, hostility, aggressiveness, anger attacks, and angry outbursts. In fact, irritability and angry outbursts are approximately twice as prevalent among patients with MD and ED (73%) than among depressed patients without ED.

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Irritability ―by unknown licensed under CC BY-SA 4.0
Adenomyosis ―sourced from Wikipedia licensed under CC BY-SA 3.0
Hyperthyroidism ―by unknown licensed under CC BY-SA 4.0
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