Generally, osteoporosis or decreased bone density affects almost all women with premature ovarian failure (POF) due to an insufficiency of estrogen (female sex hormones). Premature ovarian failure is the loss of function of the ovaries before age 40. Hormonally, POF is defined by abnormally low levels of estrogen and high levels of follicle-stimulating hormone (FSH), which demonstrate that the ovaries are no longer responding to circulating FSH by producing estrogen and developing fertile eggs.
In men, osteoporosis is often seen with testosterone deficiency, i.e. low levels of testosterone that stalls sex drive. It can also contribute to erectile dysfunction. Also, testosterone plays an important role in making sperm. Deficiency in testosteorne levels contributes to low sperm count, thus, low sperm count makes it harder to conceive a child.